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WNT10A Polyclonal Antibody (CAB14668)

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SKU:
CAB14668
$331.89

Description

Overview

Title:WNT10A Polyclonal Antibody (CAB14668)
Size:100µL
Code:CAB14668
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 158-417 of human WNT10A (NP_079492.2).
GeneID:80326
SwissProt:Q9GZT5
Synonyms:WNT10A; OODD; SSPS; STHAG4; protein Wnt-10a
Calculated MW:46kDa
Observed MW:46kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:293T
Cellular Location:Secreted, extracellular matrix, extracellular space

Antibody Images

Western blot - WNT10A Polyclonal Antibody (CAB14668)

Western blot analysis of extracts of 293T cells, using WNT10A antibody (CAB14668) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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