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TSG101 Polyclonal Antibody (CAB1692)

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CAB1692
  • Western blot - TSG101 Polyclonal Antibody (CAB1692)
  • Immunohistochemistry - TSG101 Polyclonal Antibody (CAB1692)
$331.89

Description

Overview

Title:TSG101 Polyclonal Antibody (CAB1692)
Size:100µL
Code:CAB1692
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Immunogen Information

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TSG101 (NP_006283.1).
GeneID:7251
SwissProt:Q99816
Synonyms:TSG101; TSG10; VPS23; tumor susceptibility 101
Calculated MW:31kDa/43kDa
Observed MW:44kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunohistochemistry    
Positive Samples:HeLa, MCF7, K-562, Mouse spinal cord, Rat heart, Rat lung
Cellular Location:Cytoplasm, Late endosome membrane, Membrane, Nucleus, Peripheral membrane protein

Antibody Images

Western blot - TSG101 Polyclonal Antibody (CAB1692)

Western blot analysis of extracts of various cell lines, using TSG101 antibody (CAB1692) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 40s.

Immunohistochemistry - TSG101 Polyclonal Antibody (CAB1692)

Immunohistochemistry of paraffin-embedded human liver injury using TSG101 antibody (CAB1692) at dilution of 1:100 (40x lens).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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