The cookie settings on this website are set to 'allow all cookies' to give you the very best experience. Please click Accept Cookies to continue to use the site.

SNCA Polyclonal Antibody (CAB0012)

(No reviews yet) Write a Review
SKU:
CAB0012
$331.89

Description

Overview

Title:SNCA Polyclonal Antibody (CAB0012)
Size:100µL
Code:CAB0012
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Immunogen Information

Immunogen:A synthetic peptide of human SNCA
GeneID:6622
SwissProt:P37840
Synonyms:SNCA; NACP; PARK1; PARK4; PD1; alpha-synuclein
Calculated MW:11kDa/13kDa/14kDa
Observed MW:16kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC; FC
Recommended Dilution:WB 1:200 - 1:2000; IHC 1:50 - 1:200; FC 1:20 - 1:50
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    Immunohistochemistry    Flow Cytometry    
Positive Samples:Mouse brain
Cellular Location:Cell junction, Cytoplasm, Membrane, Nucleus, Secreted, cytosol, synapse

Antibody Images

Western blot - SNCA Polyclonal Antibody (CAB0012)

Western blot analysis of extracts of mouse brain, using SNCA antibody (CAB0012).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Datasheets

Antibody DatasheetAntibody MSDS

View AllClose

Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Application:
FC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
View AllClose