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RAD23B Monoclonal Antibody (CAB6842)

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SKU:
CAB6842
$331.89

Description

Overview

Title:RAD23B Monoclonal Antibody (CAB6842)
Size:100µL
Code:CAB6842
Host Species:Mouse
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Immunogen Information

Immunogen:A synthetic peptide of human RAD23B
GeneID:5887
SwissProt:P54727
Synonyms:RAD23B; HHR23B; HR23B; P58; UV excision repair protein RAD23 homolog B
Calculated MW:35kDa/43kDa
Observed MW:57kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:200 - 1:2000
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    
Positive Samples:A-431, Mouse kidney
Cellular Location:Cytoplasm, Nucleus

Antibody Images

Western blot - RAD23B Monoclonal Antibody (CAB6842)

Western blot analysis of extracts of various cell lines, using RAD23B antibody (CAB6842).Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) (CABS003) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Monoclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Mouse
Isotype:
IgG
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