RABEP1 Polyclonal Antibody (CAB4273)

(No reviews yet) Write a Review
SKU:
CAB4273
€299.00
Frequently bought together:

Description

Antibody DatasheetAntibody MSDS

RABEP1 Polyclonal Antibody (CAB4273)

Overview

Title:RABEP1 Polyclonal Antibody (CAB4273)
Size:100µL
Code:CAB4273
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

N/A

Immunogen Information

Immunogen:A synthetic Peptide of human RABEP1
GeneID:9135
SwissProt:Q15276
Synonyms:RABEP1; RAB5EP; RABPT5; rab GTPase-binding effector protein 1
Calculated MW:95kDa/99kDa
Observed MW:114kDa

Applications

Reactivity:Mouse
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:1000
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    
Positive Samples:NIH/3T3
Cellular Location:Cytoplasm, Cytoplasmic vesicle, Early endosome, Recycling endosome

Antibody Images

Western blot - RABEP1 Polyclonal Antibody (CAB4273)

Western blot analysis of extracts of NIH/3T3 cells, using RABEP1 antibody (CAB4273).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

RABEP1 Polyclonal Antibody (CAB4273) Protein Information

UniProt Protein Function:RABEP1: Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: recycling endosome; intracellular membrane-bound organelle; endocytic vesicle; early endosome; endosome

Molecular Function:protein binding; protein homodimerization activity; growth factor activity; GTPase activator activity

Biological Process: vesicle-mediated transport; protein transport; apoptosis; endocytosis; positive regulation of GTPase activity

UniProt Code:Q15276
NCBI GenInfo Identifier:116242743
NCBI Gene ID:9135
NCBI Accession:Q15276.2
UniProt Secondary Accession:Q15276,O95369, Q8IVX3, B2RAG7,
UniProt Related Accession:Q15276
Molecular Weight:862
NCBI Full Name:Rab GTPase-binding effector protein 1
NCBI Synonym Full Names:rabaptin, RAB GTPase binding effector protein 1
NCBI Official Symbol:RABEP1  
NCBI Official Synonym Symbols:RAB5EP; RABPT5  
NCBI Protein Information:rab GTPase-binding effector protein 1; rabaptin-4; rabaptin-5; neurocrescin; rabaptin-5alpha; renal carcinoma antigen NY-REN-17
UniProt Protein Name:Rab GTPase-binding effector protein 1
UniProt Synonym Protein Names:Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17
Protein Family:Rab GTPase-binding effector protein
UniProt Gene Name:RABEP1  
UniProt Entry Name:RABE1_HUMAN
View AllClose

Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
View AllClose