The cookie settings on this website are set to 'allow all cookies' to give you the very best experience. Please click Accept Cookies to continue to use the site.

RAB7A Polyclonal Antibody (CAB12344)

(No reviews yet) Write a Review
SKU:
CAB12344
$331.89

Description

Overview

Title:RAB7A Polyclonal Antibody (CAB12344)
Size:100µL
Code:CAB12344
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Immunogen Information

Immunogen:Recombinant protein of human RAB7A
GeneID:7879
SwissProt:P51149
Synonyms:RAB7A; PRO2706; RAB7; ras-related protein Rab-7a
Calculated MW:23kDa
Observed MW:23kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC; FC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:100; FC 1:20 - 1:50
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    Immunohistochemistry    Flow Cytometry    
Positive Samples:A-431, HeLa
Cellular Location:Cytoplasmic side, Cytoplasmic vesicle, Late endosome membrane, Lipid droplet, Lysosome membrane, Melanosome membrane, Peripheral membrane protein, autophagosome membrane, phagosome membrane

Antibody Images

Western blot - RAB7A Polyclonal Antibody (CAB12344)

Western blot analysis of extracts of various cell lines, using RAB7A antibody (CAB12344).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Datasheets

Antibody DatasheetAntibody MSDS

View AllClose

Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Application:
FC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
View AllClose