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PINK1 Polyclonal Antibody (CAB11435)

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CAB11435
  • Western blot - PINK1 Polyclonal Antibody (CAB11435)
  • Immunofluorescence - PINK1 Polyclonal Antibody (CAB11435)
$331.89

Description

Overview

Title:PINK1 Polyclonal Antibody (CAB11435)
Size:100µL
Code:CAB11435
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).
GeneID:65018
SwissProt:Q9BXM7
Synonyms:PINK1; BRPK; PARK6; PTEN induced putative kinase 1
Calculated MW:30kDa/62kDa
Observed MW:70kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC; IF
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunohistochemistry    Immunofluorescence    
Positive Samples:SW480, PC-12, Mouse kidney, Mouse brain, Mouse heart, Mouse skeletal muscle, Rat brain
Cellular Location:Cytoplasm, Mitochondrion outer membrane, Single-pass membrane protein, cytosol

Antibody Images

Western blot - PINK1 Polyclonal Antibody (CAB11435)

Western blot analysis of extracts of various cell lines, using PINK1 antibody (CAB11435) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

Immunofluorescence - PINK1 Polyclonal Antibody (CAB11435)

Immunofluorescence analysis of HeLa cells using PINK1 antibody (CAB11435). Blue: DAPI for nuclear staining.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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