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Phospho-GSK3B-Y216 pAb (CABP0512)

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SKU:
CABP0512
€429.00

Description

Overview

Title:Phospho-GSK3B-Y216 pAb (CABP0512)
Size:100µL
Code:CABP0512
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Immunogen:A phospho specific peptide corresponding to residues surrounding Y216 of human GSK3B
GeneID:2932
SwissProt:P49841
Synonyms:GSK3B; glycogen synthase kinase-3 beta
Calculated MW:46kDa/48kDa
Observed MW:50kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:293
Cellular Location:Cell membrane, Cytoplasm, Nucleus

Antibody Images

Western blot - Phospho-GSK3B-Y216 pAb (CABP0512)

Western blot analysis of extracts of 293T cells, using Phospho-GSK3B-Y216 antibody (CABP0512) at 1:1000 dilution. 293T cells were treated by Insulin (100nM) for 10 minutes or treated by 10% FBS for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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