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Phospho-BCL2L11-S69 pAb (CABP0313)

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CABP0313
  • Immunohistochemistry - Phospho-BCL2L11-S69 pAb (CABP0313)
  • Immunofluorescence - Phospho-BCL2L11-S69 pAb (CABP0313)
$476.19

Description

Overview

Title:Phospho-BCL2L11-S69 pAb (CABP0313)
Size:100µL
Code:CABP0313
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Immunogen Information

Immunogen:A phospho specific peptide corresponding to residues surrounding S69 of human BCL2L11
GeneID:10018
SwissProt:O43521
Synonyms:BCL2L11; BAM; BIM; BOD; BCL2 like 11
Calculated MW:4-22kDa
Observed MW:N/A

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:IHC; IF
Recommended Dilution:IHC 1:50 - 1:100; IF 1:100 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunohistochemistry    Immunofluorescence    
Positive Samples:N/A
Cellular Location:Endomembrane system, Mitochondrion, Peripheral membrane protein

Antibody Images

Immunohistochemistry - Phospho-BCL2L11-S69 pAb (CABP0313)

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-BCL2L11-S69 antibody (CABP0313).

Immunofluorescence - Phospho-BCL2L11-S69 pAb (CABP0313)

Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-BCL2L11-S69 antibody (CABP0313).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
IHC
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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