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PEX12 Polyclonal Antibody (CAB16062)

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SKU:
CAB16062
$331.89

Description

Overview

Title:PEX12 Polyclonal Antibody (CAB16062)
Size:100µL
Code:CAB16062
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 290-359 of human PEX12 (NP_000277.1).
GeneID:5193
SwissProt:O00623
Synonyms:PEX12; PAF-3; PBD3A; peroxisome assembly protein 12
Calculated MW:40kDa
Observed MW:41kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:U-87MG, MCF7
Cellular Location:Multi-pass membrane protein, Peroxisome membrane

Antibody Images

Western blot - PEX12 Polyclonal Antibody (CAB16062)

Western blot analysis of extracts of various cell lines, using PEX12 antibody (CAB16062) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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