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Phosducin Polyclonal Antibody (CAB8447)

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SKU:
CAB8447
€299.00

Description

Overview

Title:PDC Polyclonal Antibody (CAB8447)
Size:100µL
Code:CAB8447
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_002588.3).
GeneID:5132
SwissProt:P20941
Synonyms:PDC; MEKA; PHD; PhLOP; PhLP; phosducin
Calculated MW:22kDa/28kDa/32kDa
Observed MW:28kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunohistochemistry    
Positive Samples:LO2, 22Rv1, 293T
Cellular Location:Cell projection, Cytoplasm, Nucleus, Nucleus, Photoreceptor inner segment, cilium, cytosol, photoreceptor outer segment

Antibody Images

Western blot - PDC Polyclonal Antibody (CAB8447)

Western blot analysis of extracts of various cell lines, using PDC antibody (CAB8447) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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