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PARK2 Polyclonal Antibody (CAB11172)

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CAB11172
  • Western blot - PARK2 Polyclonal Antibody (CAB11172)
  • Immunofluorescence - PARK2 Polyclonal Antibody (CAB11172)
€299.00

Description

Overview

Title:PARK2 Polyclonal Antibody (CAB11172)
Size:100µL
Code:CAB11172
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PARK2 (AAH22014.1).
GeneID:5071
SwissProt:O60260
Synonyms:PRKN; AR-JP; LPRS2; PARK2; PDJ; E3 ubiquitin-protein ligase parkin
Calculated MW:23kDa/30-51kDa
Observed MW:52kDa

Applications

Reactivity:Human, Mouse
Tested Applications:WB; IF
Recommended Dilution:WB 1:500 - 1:2000; IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunofluorescence    
Positive Samples:Mouse brain, Mouse liver
Cellular Location:Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, cytosol

Antibody Images

Western blot - PARK2 Polyclonal Antibody (CAB11172)

Western blot analysis of extracts of various cell lines, using PARK2 antibody (CAB11172) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Immunofluorescence - PARK2 Polyclonal Antibody (CAB11172)

Immunofluorescence analysis of A549 cells using PARK2 antibody (CAB11172).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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