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Nyctalopin Polyclonal Antibody (CAB7830)

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SKU:
CAB7830
  • Western blot - NYX Polyclonal Antibody (CAB7830)
  • Immunohistochemistry - NYX Polyclonal Antibody (CAB7830)
  • Immunohistochemistry - NYX Polyclonal Antibody (CAB7830)
€299.00

Description

Overview

Title:NYX Polyclonal Antibody (CAB7830)
Size:100µL
Code:CAB7830
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1).
GeneID:60506
SwissProt:Q9GZU5
Synonyms:NYX; CLRP; CSNB1; CSNB1A; CSNB4; NBM1; nyctalopin
Calculated MW:52kDa
Observed MW:52kDa

Applications

Reactivity:Human, Mouse
Tested Applications:WB; IHC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunohistochemistry    
Positive Samples:293T
Cellular Location:Secreted, extracellular matrix, extracellular space

Antibody Images

Western blot - NYX Polyclonal Antibody (CAB7830)

Western blot analysis of extracts of 293T cells, using NYX antibody (CAB7830) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

Immunohistochemistry - NYX Polyclonal Antibody (CAB7830)

Immunohistochemistry of paraffin-embedded human prostate using NYX antibody (CAB7830) at dilution of 1:100 (40x lens).

Immunohistochemistry - NYX Polyclonal Antibody (CAB7830)

Immunohistochemistry of paraffin-embedded mouse lung using NYX antibody (CAB7830) at dilution of 1:100 (40x lens).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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