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MAML1 Polyclonal Antibody (CAB17060)

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SKU:
CAB17060
$331.89

Description

Overview

Title:MAML1 Polyclonal Antibody (CAB17060)
Size:100µL
Code:CAB17060
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Immunogen Information

Immunogen:Recombinant protein of human MAML1.
GeneID:9794
SwissProt:Q92585
Synonyms:MAML1; Mam-1; Mam1; mastermind-like protein 1
Calculated MW:108kDa
Observed MW:120kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:HeLa, Jurkat, mouse brain, rat brain
Cellular Location:N/A

Antibody Images

Western blot - MAML1 Polyclonal Antibody (CAB17060)

Western blot analysis of extracts of various cell lines, using MAML1 antibody (CAB17060) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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