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[KO Validated] PRDX2 Polyclonal Antibody (CAB1919)

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CAB1919
  • Western blot - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)
  • Western blot - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)
  • Immunofluorescence - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)
$553.89

Description

Overview

Title:[KO Validated] PRDX2 Polyclonal Antibody (CAB1919)
Size:100µL
Code:CAB1919
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1).
GeneID:7001
SwissProt:P32119
Synonyms:PRDX2; HEL-S-2a; NKEF-B; NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA; peroxiredoxin-2
Calculated MW:15kDa/21kDa
Observed MW:20kDa

Applications

Reactivity:Human, Mouse
Tested Applications:WB; IF
Recommended Dilution:WB 1:500 - 1:2000; IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunofluorescence    
Positive Samples:SW480, 22Rv1, HepG2, K-562, BT-474, Mouse brain, Mouse kidney
Cellular Location:Cytoplasm

Antibody Images

Western blot - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)

Western blot analysis of extracts of various cell lines, using PRDX2 antibody (CAB1919) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Western blot - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)

Western blot analysis of extracts from normal (control) and PRDX2 knockout (KO) 293T cells, using PRDX2 antibody (CAB1919) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

Immunofluorescence - [KO Validated] PRDX2 Polyclonal Antibody (CAB1919)

Immunofluorescence analysis of HeLa cells using PRDX2 antibody (CAB1919).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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