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KEAP1 Polyclonal Antibody (CAB17061)

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SKU:
CAB17061
$331.89

Description

Overview

Title:KEAP1 Polyclonal Antibody (CAB17061)
Size:100µL
Code:CAB17061
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Immunogen Information

Immunogen:A synthetic peptide of human KEAP1.
GeneID:9817
SwissProt:Q14145
Synonyms:KEAP1; INrf2; KLHL19; kelch-like ECH-associated protein 1
Calculated MW:69kDa
Observed MW:Refer to figures

Applications

Reactivity:Mouse
Tested Applications:WB; IF; IP
Recommended Dilution:WB 1:500 - 1:2000; IF 1:50 - 1:100; IP 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunofluorescence    Immunoprecipitation    
Positive Samples:mouse brain
Cellular Location:N/A

Antibody Images

Western blot - KEAP1 Polyclonal Antibody (CAB17061)

Western blot analysis of extracts of mouse brain, using KEAP1 antibody (CAB17061) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IF
Application:
IP
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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