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IRGM Polyclonal Antibody (CAB10968)

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SKU:
CAB10968
€299.00

Description

Overview

Title:IRGM Polyclonal Antibody (CAB10968)
Size:100µL
Code:CAB10968
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen Information

Immunogen:A synthetic peptide of human IRGM
GeneID:345611
SwissProt:A1A4Y4
Synonyms:IRGM; IFI1; IRGM1; LRG-47; LRG47; immunity related GTPase M
Calculated MW:20kDa
Observed MW:34kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IHC
Recommended Dilution:WB 1:500 - 1:1000; IHC 1:20 - 1:50
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    Immunohistochemistry    
Positive Samples:Mouse kidney, Mouse brain, Rat lung
Cellular Location:Cell membrane, Cell projection, Cytoplasmic vesicle, Golgi apparatus membrane, autophagosome membrane, phagocytic cup, phagosome membrane

Antibody Images

Western blot - IRGM Polyclonal Antibody (CAB10968)

Western blot analysis of extracts of various cell lines, using IRGM antibody (CAB10968) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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