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Frizzled-3 Polyclonal Antibody (CAB10063)

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SKU:
CAB10063
€299.00

Description

Overview

Title:FZD3 Polyclonal Antibody (CAB10063)
Size:100µL
Code:CAB10063
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 23-205 of human FZD3 (NP_059108.1).
GeneID:7976
SwissProt:Q9NPG1
Synonyms:FZD3; Fz-3; frizzled-3
Calculated MW:76kDa
Observed MW:76kDa

Applications

Reactivity:Human, Mouse
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:SH-SY5Y, HeLa, MCF-7, Mouse brain, Mouse kidney
Cellular Location:Apical cell membrane, Cell membrane, Cell surface, Membrane, Multi-pass membrane protein

Antibody Images

Western blot - FZD3 Polyclonal Antibody (CAB10063)

Western blot analysis of extracts of various cell lines, using FZD3 antibody (CAB10063) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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