CGGBP1 Polyclonal Antibody (CAB4231)

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CAB4231
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Description

Antibody DatasheetAntibody MSDS

CGGBP1 Polyclonal Antibody (CAB4231)

Overview

Title:CGGBP1 Polyclonal Antibody (CAB4231)
Size:100µL
Code:CAB4231
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

N/A

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CGGBP1 (NP_003654.3).
GeneID:8545
SwissProt:Q9UFW8
Synonyms:CGGBP1; CGGBP; p20-CGGBP; CGG triplet repeat-binding protein 1
Calculated MW:18kDa
Observed MW:20kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:Raji, HeLa, 293T, Jurkat
Cellular Location:Nucleus

Antibody Images

Western blot - CGGBP1 Polyclonal Antibody (CAB4231)

Western blot analysis of extracts of various cell lines, using CGGBP1 antibody (CAB4231) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

CGGBP1 Polyclonal Antibody (CAB4231) Protein Information

UniProt Protein Function:CGGBP1: Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.
UniProt Protein Details:

Protein type:Transcription regulation

Chromosomal Location of Human Ortholog: 3p11.1

Cellular Component: nucleoplasm; nucleus

Molecular Function:double-stranded DNA binding; protein binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter

NCBI Summary:CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008]
UniProt Code:Q9UFW8
NCBI GenInfo Identifier:116243045
NCBI Gene ID:8545
NCBI Accession:Q9UFW8.2
UniProt Secondary Accession:Q9UFW8,O15183, D3DU38,
UniProt Related Accession:Q9UFW8
Molecular Weight:18,820 Da
NCBI Full Name:CGG triplet repeat-binding protein 1
NCBI Synonym Full Names:CGG triplet repeat binding protein 1
NCBI Official Symbol:CGGBP1  
NCBI Official Synonym Symbols:CGGBP; p20-CGGBP  
NCBI Protein Information:CGG triplet repeat-binding protein 1
UniProt Protein Name:CGG triplet repeat-binding protein 1
UniProt Synonym Protein Names:20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein
Protein Family:CGG triplet repeat-binding protein
UniProt Gene Name:CGGBP1  
UniProt Entry Name:CGBP1_HUMAN
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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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