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CDS1 Polyclonal Antibody (CAB13758)

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SKU:
CAB13758
$331.89

Description

Overview

Title:CDS1 Polyclonal Antibody (CAB13758)
Size:100µL
Code:CAB13758
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CDS1 (NP_001254.2).
GeneID:1040
SwissProt:Q92903
Synonyms:CDS1; CDS; CDP-diacylglycerol synthase 1
Calculated MW:53kDa
Observed MW:57kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:OVCAR3, U-87MG, 293T
Cellular Location:Endoplasmic reticulum membrane, Multi-pass membrane protein

Antibody Images

Western blot - CDS1 Polyclonal Antibody (CAB13758)

Western blot analysis of extracts of various cell lines, using CDS1 antibody (CAB13758) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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