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CDC25A Polyclonal Antibody (CAB2687)

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SKU:
CAB2687
€299.00

Description

Overview

Title:CDC25A Polyclonal Antibody (CAB2687)
Size:100µL
Code:CAB2687
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Immunogen:Recombinant protein of human CDC25A
GeneID:993
SwissProt:P30304
Synonyms:CDC25A; CDC25A2; cell division cycle 25A
Calculated MW:54kDa/59kDa
Observed MW:59kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:Mouse heart
Cellular Location:N/A

Antibody Images

Western blot - CDC25A Polyclonal Antibody (CAB2687)

Western blot analysis of extracts of mouse heart, using CDC25A antibody (CAB2687).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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