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CDC25A Polyclonal Antibody (CAB1173)

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SKU:
CAB1173
  • Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)
  • Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)
  • Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)
  • Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)
  • Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)
€299.00

Description

Overview

Title:CDC25A Polyclonal Antibody (CAB1173)
Size:100µL
Code:CAB1173
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 235-484 of human CDC25A (NP_963861.1).
GeneID:993
SwissProt:P30304
Synonyms:CDC25A; CDC25A2; cell division cycle 25A
Calculated MW:54kDa/59kDa
Observed MW:N/A

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:IHC; IF
Recommended Dilution:IHC 1:50 - 1:200; IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunohistochemistry    Immunofluorescence    
Positive Samples:N/A
Cellular Location:N/A

Antibody Images

Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)

Immunohistochemistry of paraffin-embedded rat liver using CDC25A antibody (CAB1173) at dilution of 1:100 (40x lens).

Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)

Immunohistochemistry of paraffin-embedded rat kidney using CDC25A antibody (CAB1173) at dilution of 1:100 (40x lens).

Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)

Immunohistochemistry of paraffin-embedded rat heart using CDC25A antibody (CAB1173) at dilution of 1:100 (40x lens).

Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)

Immunohistochemistry of paraffin-embedded human liver injury using CDC25A antibody (CAB1173) at dilution of 1:100 (40x lens).

Immunohistochemistry - CDC25A Polyclonal Antibody (CAB1173)

Immunohistochemistry of paraffin-embedded mouse kidney using CDC25A antibody (CAB1173) at dilution of 1:100 (40x lens).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
IHC
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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