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Cyclin-A2 Polyclonal Antibody (CAB0034)

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SKU:
CAB0034
€299.00

Description

Overview

Title:CCNA2 Polyclonal Antibody (CAB0034)
Size:100µL
Code:CAB0034
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

Immunogen Information

Immunogen:A synthetic peptide of human CCNA2
GeneID:890
SwissProt:P20248
Synonyms:CCNA2; CCN1; CCNA; cyclin-A2
Calculated MW:48kDa
Observed MW:56kDa

Applications

Reactivity:Human
Tested Applications:WB; IHC; FC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:100; FC 1:20 - 1:50
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Application Key:Western blotting    Immunohistochemistry    Flow Cytometry    
Positive Samples:K-562
Cellular Location:Cytoplasm, Nucleus

Antibody Images

Western blot - CCNA2 Polyclonal Antibody (CAB0034)

Western blot analysis of extracts of K-562 cells, using CCNA2 antibody (CAB0034).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Application:
FC
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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