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CASP7 Polyclonal Antibody (CAB0716)

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SKU:
CAB0716
$331.89

Description

Overview

Title:CASP7 Polyclonal Antibody (CAB0716)
Size:100µL
Code:CAB0716
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human CASP7 (NP_001218.1).
GeneID:840
SwissProt:P55210
Synonyms:CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; caspase-7
Calculated MW:28kDa/31kDa/34kDa/37kDa
Observed MW:Refer to figures

Applications

Reactivity:Human, Rat
Tested Applications:IHC; IP
Recommended Dilution:IHC 1:50 - 1:100; IP 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunohistochemistry    Immunoprecipitation    
Positive Samples:N/A
Cellular Location:Cytoplasm

Antibody Images

Immunohistochemistry - CASP7 Polyclonal Antibody (CAB0716)

Immunohistochemistry of paraffin-embedded rat heart using CASP7 antibody (CAB0716) at dilution of 1:100 (40x lens).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
IHC
Application:
IP
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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