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CABLES1 Polyclonal Antibody (CAB10335)

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SKU:
CAB10335
€299.00

Description

Overview

Title:CABLES1 Polyclonal Antibody (CAB10335)
Size:100µL
Code:CAB10335
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1).
GeneID:91768
SwissProt:Q8TDN4
Synonyms:CABLES1; CABL1; CABLES; HsT2563; IK3-1; Cdk5 and Abl enzyme substrate 1
Calculated MW:15kDa/34kDa/41kDa/67kDa
Observed MW:68kDa

Applications

Reactivity:Human, Mouse
Tested Applications:WB
Recommended Dilution:WB 1:1000 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:MCF-7, HT-29, A-549, HL-60, HeLa, Mouse brain
Cellular Location:Cytoplasm, Nucleus

Antibody Images

Western blot - CABLES1 Polyclonal Antibody (CAB10335)

Western blot analysis of extracts of various cell lines, using CABLES1 antibody (CAB10335) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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