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BID Polyclonal Antibody (CAB0210)

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SKU:
CAB0210
€299.00

Description

Overview

Title:BID Polyclonal Antibody (CAB0210)
Size:100µL
Code:CAB0210
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Immunogen Information

Immunogen:Recombinant protein of human BID
GeneID:637
SwissProt:P55957
Synonyms:BID; FP497; BH3-interacting domain death agonist
Calculated MW:11kDa/14kDa/21kDa/26kDa
Observed MW:22kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:HL-60
Cellular Location:Cytoplasm, Mitochondrion membrane, Mitochondrion membrane

Antibody Images

Western blot - BID Polyclonal Antibody (CAB0210)

Western blot analysis of extracts of HL-60 cells, using BID Antibody (CAB0210).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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