BATF3 Polyclonal Antibody (CAB14906)

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CAB14906
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Description

Antibody DatasheetAntibody MSDS

BATF3 Polyclonal Antibody (CAB14906)

Overview

Title:BATF3 Polyclonal Antibody (CAB14906)
Size:100µL
Code:CAB14906
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1).
GeneID:55509
SwissProt:Q9NR55
Synonyms:BATF3; JDP1; JUNDM1; SNFT; basic leucine zipper ATF-like transcription factor 3
Calculated MW:14kDa
Observed MW:14kDa

Applications

Reactivity:Rat
Tested Applications:WB; IHC
Recommended Dilution:WB 1:500 - 1:2000; IHC 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunohistochemistry    
Positive Samples:Rat spleen
Cellular Location:Nucleus

Antibody Images

Western blot - BATF3 Polyclonal Antibody (CAB14906)

Western blot analysis of extracts of rat spleen, using BATF3 antibody (CAB14906) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

BATF3 Polyclonal Antibody (CAB14906) Protein Information

UniProt Protein Function:BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: nucleus

Molecular Function:protein binding; transcription corepressor activity; transcription factor activity

Biological Process: myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; response to virus; transcription from RNA polymerase II promoter

NCBI Summary:This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
UniProt Code:Q9NR55
NCBI GenInfo Identifier:74752916
NCBI Gene ID:55509
NCBI Accession:Q9NR55.1
UniProt Secondary Accession:Q9NR55,Q9D275, P97876,
UniProt Related Accession:Q9NR55
Molecular Weight:14,468 Da
NCBI Full Name:Basic leucine zipper transcriptional factor ATF-like 3
NCBI Synonym Full Names:basic leucine zipper ATF-like transcription factor 3
NCBI Official Symbol:BATF3  
NCBI Official Synonym Symbols:JDP1; SNFT; JUNDM1  
NCBI Protein Information:basic leucine zipper transcriptional factor ATF-like 3
UniProt Protein Name:Basic leucine zipper transcriptional factor ATF-like 3
UniProt Synonym Protein Names:21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
Protein Family:Basic leucine zipper transcriptional factor
UniProt Gene Name:BATF3  
UniProt Entry Name:BATF3_HUMAN
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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IHC
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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