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BANK1 Polyclonal Antibody (CAB10312)

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SKU:
CAB10312
$331.89

Description

Overview

Title:BANK1 Polyclonal Antibody (CAB10312)
Size:100µL
Code:CAB10312
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1, 4, 5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 516-785 of human BANK1 (NP_060405.4).
GeneID:55024
SwissProt:Q8NDB2
Synonyms:BANK1; BANK; B-cell scaffold protein with ankyrin repeats
Calculated MW:73kDa/86kDa/88kDa/89kDa
Observed MW:80kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:1000 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:B-cell, Raji, U-87MG, A-549, 22Rv1, HepG2, Mouse liver, Rat liver
Cellular Location:N/A

Antibody Images

Western blot - BANK1 Polyclonal Antibody (CAB10312)

Western blot analysis of extracts of various cell lines, using BANK1 antibody (CAB10312) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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