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BAIAP2L1 Polyclonal Antibody (CAB15173)

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SKU:
CAB15173
$331.89

Description

Overview

Title:BAIAP2L1 Polyclonal Antibody (CAB15173)
Size:100µL
Code:CAB15173
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human BAIAP2L1 (NP_061330.2).
GeneID:55971
SwissProt:Q9UHR4
Synonyms:BAIAP2L1; IRTKS; BAI1 associated protein 2 like 1
Calculated MW:56kDa
Observed MW:N/A

Applications

Reactivity:Human
Tested Applications:IF
Recommended Dilution:IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunofluorescence    
Positive Samples:N/A
Cellular Location:Cytoplasm, cytoskeleton

Antibody Images

Immunofluorescence - BAIAP2L1 Polyclonal Antibody (CAB15173)

Immunofluorescence analysis of U2OS cells using BAIAP2L1 antibody (CAB15173) at dilution of 1:100. Blue: DAPI for nuclear staining.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
IF
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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