Description
Title: | BAG6 Polyclonal Antibody (CAB2010) | |
Size: | 100µL | |
Code: | CAB2010 | |
Host Species: | Rabbit | |
Purification: | Affinity purification | |
Isotype: | IgG |
Background
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BAG6 (NP_001092004.1). |
GeneID: | 7917 |
SwissProt: | P46379 |
Synonyms: | BAG6; BAG-6; BAT3; D6S52E; G3; BCL2 associated athanogene 6 |
Calculated MW: | 96kDa/113kDa/118kDa/119kDa/122kDa |
Observed MW: | 160kDa |
Applications
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Application Key: | Western blotting |
Positive Samples: | 293T, HeLa, Mouse testis, Rat testis |
Cellular Location: | Cytoplasm, Nucleus, cytosol |
Antibody Images
Western blot analysis of extracts of various cell lines, using BAG6 antibody (CAB2010) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s. |
Additional Information
Antibody Type: |
Polyclonal |
Application: |
WB |
Reactivity: |
Human |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |