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ATG7 Polyclonal Antibody (CAB7360)

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SKU:
CAB7360
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
  • Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)
$331.89

Description

Overview

Title:ATG7 Polyclonal Antibody (CAB7360)
Size:100µL
Code:CAB7360
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 500-676 of human ATG7 (NP_001129503.2).
GeneID:10533
SwissProt:O95352
Synonyms:ATG7; APG7-LIKE; APG7L; GSA7; autophagy related 7
Calculated MW:68kDa/75kDa/77kDa
Observed MW:N/A

Applications

Reactivity:Human
Tested Applications:IHC
Recommended Dilution:IHC 1:50 - 1:100
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Immunohistochemistry    
Positive Samples:N/A
Cellular Location:Cytoplasm, Preautophagosomal structure

Antibody Images

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human stomach using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human lung cancer using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human liver cancer using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human colon carcinoma using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human breast cancer using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Immunohistochemistry - ATG7 Polyclonal Antibody (CAB7360)

Immunohistochemistry of paraffin-embedded human gastric cancer using ATG7 antibody (CAB7360) at dilution of 1:100 (40x lens).

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
IHC
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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