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ATG16L1 Polyclonal Antibody (CAB11969)

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SKU:
CAB11969
$331.89

Description

Overview

Title:ATG16L1 Polyclonal Antibody (CAB11969)
Size:100µL
Code:CAB11969
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ATG16L1 (NP_110430.5).
GeneID:55054
SwissProt:Q676U5
Synonyms:ATG16L1; APG16L; ATG16A; ATG16L; IBD10; WDR30; autophagy related 16 like 1
Calculated MW:47kDa/49kDa/53kDa/66kDa/68kDa
Observed MW:72kDa

Applications

Reactivity:Human
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:HT-29, MCF7, HeLa
Cellular Location:Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane

Antibody Images

Western blot - ATG16L1 Polyclonal Antibody (CAB11969)

Western blot analysis of extracts of various cell lines, using ATG16L1 antibody (CAB11969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
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