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ANG Polyclonal Antibody (CAB13465)

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SKU:
CAB13465
$331.89

Description

Overview

Title:ANG Polyclonal Antibody (CAB13465)
Size:100µL
Code:CAB13465
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-147 of human ANG (NP_001091046.1).
GeneID:283
SwissProt:P03950
Synonyms:ANG; ALS9; HEL168; RAA1; RNASE4; RNASE5; angiogenin
Calculated MW:16kDa
Observed MW:14KDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:LO2, HeLa, H460, B-cell, Mouse liver, Rat liver
Cellular Location:Nucleus, Secreted, basement membrane, extracellular matrix, extracellular space, nucleolus

Antibody Images

Western blot - ANG Polyclonal Antibody (CAB13465)

Western blot analysis of extracts of various cell lines, using ANG antibody (CAB13465) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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