|Title:||AF/LE Purified Human CD40 Monoclonal Antibody|
|Volume Per Test:||1mg/mL|
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).
|Conjugation:||Azide Free/Low endotoxin|
|Tested Applications:||Stim, FA, FC|
|Recommended Dilution:||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ? 2.0 µg per 10e6 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.|
|Storage Buffer:||0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (<0.002EU/?g) as Determined by LAL gel clotting assay. Purity is >95% as determined by SDS-PAGE |
|Storage:||Store at 2~8?. Do not freeze. |