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AF/LE Purified Human CD11a Monoclonal Antibody [R7-1](AGEL2085)

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SKU:
AGEL2085
$911.31

Description

Overview:

Title:AF/LE Purified Human CD11a Monoclonal Antibody
Host Species:Mouse
Size:1 mg
Volume Per Test:1mg/mL

Background:

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1alpha chain and integrin alphaL subunit. CD11a non-covalently associates with integrin beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Antibody Information:

Isotype:IgG2a, ?
GeneID:3683
SwissProt:P20701
Synonyms:Integrin alpha-L,LFA-1A,CD11A,ITGAL
Clone:R7-1
Conjugation:Azide Free/Low endotoxin

Applications:

Reactivity:Human
Tested Applications:FA, FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ? 2.0 µg per 10e6 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (<0.002EU/?g) as Determined by LAL gel clotting assay. Purity is >95% as determined by SDS-PAGE
Storage:Store at 2~8?. Do not freeze.
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