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ADAMTS13 Polyclonal Antibody (CAB8482)

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SKU:
CAB8482
$331.89

Description

Overview

Title:ADAMTS13 Polyclonal Antibody (CAB8482)
Size:100µL
Code:CAB8482
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.

Immunogen Information

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human ADAMTS13 (NP_620594.1).
GeneID:11093
SwissProt:Q76LX8
Synonyms:ADAMTS13; ADAM-TS13; ADAMTS-13; C9orf8; VWFCP; vWF-CP; ADAM metallopeptidase with thrombospondin type 1 motif 13
Calculated MW:39kDa/144kDa/147kDa/153kDa
Observed MW:156kDa, 157kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB; IF
Recommended Dilution:WB 1:500 - 1:2000; IF 1:50 - 1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    Immunofluorescence    
Positive Samples:HepG2, LO2, 22Rv1, U-251MG, Mouse liver
Cellular Location:Secreted

Antibody Images

Western blot - ADAMTS13 Polyclonal Antibody (CAB8482)

Western blot analysis of extracts of various cell lines, using ADAMTS13 antibody (CAB8482) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Application:
IF
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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