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ACVRL1 Polyclonal Antibody (CAB1791)

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SKU:
CAB1791
€299.00

Description

Overview

Title:ACVRL1 Polyclonal Antibody (CAB1791)
Size:100µL
Code:CAB1791
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Immunogen Information

Immunogen:Recombinant protein of human ACVRL1
GeneID:94
SwissProt:P37023
Synonyms:ACVRL1; ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I; activin A receptor like type 1
Calculated MW:56kDa
Observed MW:65kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:SH-SY5Y, HL-60, MCF-7, Jurkat, Mouse lung, Mouse heart, Mouse liver, Rat brain
Cellular Location:Membrane, Single-pass type I membrane protein

Antibody Images

Western blot - ACVRL1 Polyclonal Antibody (CAB1791)

Western blot analysis of extracts of various cell lines, using ACVRL1 antibody (CAB1791) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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