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ACMSD Polyclonal Antibody (CAB15953)

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SKU:
CAB15953
$331.89

Description

Overview

Title:ACMSD Polyclonal Antibody (CAB15953)
Size:100µL
Code:CAB15953
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Immunogen Information

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human ACMSD (NP_612199.2).
GeneID:130013
SwissProt:Q8TDX5
Synonyms:ACMSD; aminocarboxymuconate semialdehyde decarboxylase
Calculated MW:31kDa/38kDa
Observed MW:38kDa

Applications

Reactivity:Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:Mouse kidney, Mouse liver, Rat kidney
Cellular Location:N/A

Antibody Images

Western blot - ACMSD Polyclonal Antibody (CAB15953)

Western blot analysis of extracts of various cell lines, using ACMSD antibody (CAB15953) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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