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ACKR3 Polyclonal Antibody (CAB12712)

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SKU:
CAB12712
$331.89

Description

Overview

Title:ACKR3 Polyclonal Antibody (CAB12712)
Size:100µL
Code:CAB12712
Host Species:Rabbit
Purification:Affinity purification
Isotype:IgG

Background

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Immunogen Information

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACKR3 (NP_064707.1).
GeneID:57007
SwissProt:P25106
Synonyms:ACKR3; CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1; atypical chemokine receptor 3
Calculated MW:41kDa
Observed MW:55kDa

Applications

Reactivity:Human, Mouse, Rat
Tested Applications:WB
Recommended Dilution:WB 1:500 - 1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Key:Western blotting    
Positive Samples:Raji, A-549, U-87MG, Mouse lung, Mouse brain, Rat brain
Cellular Location:Cell membrane, Cytoplasm, Early endosome, Multi-pass membrane protein, Recycling endosome, perinuclear region

Antibody Images

Western blot - ACKR3 Polyclonal Antibody (CAB12712)

Western blot analysis of extracts of various cell lines, using ACKR3 antibody (CAB12712) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.

Datasheets

Antibody DatasheetAntibody MSDS

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Additional Information

Antibody Type:
Polyclonal
Application:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
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