ACADM Polyclonal Antibody (CAB1873)
- SKU:
- CAB1873
Description
| Title: | ACADM Polyclonal Antibody (CAB1873) | |
| Size: | 100µL | |
| Code: | CAB1873 | |
| Host Species: | Rabbit | |
| Purification: | Affinity purification | |
| Isotype: | IgG |
Background
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1). |
| GeneID: | 34 |
| SwissProt: | P11310 |
| Synonyms: | ACADM; ACAD1; MCAD; MCADH; acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| Calculated MW: | 46kDa/47kDa |
| Observed MW: | 46kDa |
Applications
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB; IHC; IF |
| Recommended Dilution: | WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Application Key: | Western blotting Immunohistochemistry Immunofluorescence |
| Positive Samples: | HT-29, HepG2, U-251MG, K562, Mouse liver, Mouse kidney, Mouse brain, Mouse heart, Rat liver |
| Cellular Location: | Mitochondrion matrix |
Antibody Images
| Western blot analysis of extracts of various cell lines, using ACADM antibody (CAB1873) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s. |
| Immunofluorescence analysis of HeLa cells using ACADM antibody (CAB1873) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
Datasheets
Additional Information
Antibody Type: |
Polyclonal |
Application: |
WB |
Application: |
IHC |
Application: |
IF |
Reactivity: |
Human |
Reactivity: |
Mouse |
Reactivity: |
Rat |
Host Species: |
Rabbit |
Isotype: |
IgG |
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